How To Stay Safe Around Your University Campus This Autumn/Winter

University can be the best part of your life. Letting certain things spoil that due to carelessness or a lack of responsibility can seriously damage your time in higher education. As the days get shorter and the nights darker, here at Essay Writing Service we know just how crucial staying safe and looking after yourself around campus is. Always walk in open spaces at night Be aware of your surroundings no matter what the situation and avoid walking in unfamiliar places at night. Open spaces which are likely to have more people around tend to be safer; if something happens someone is likely to see and come to help. Avoid walking through unlit public areas You may always have a route into campus through a park or wooded area but this should be off limits at night. Many wooded areas tend to be poorly lit and provide coverage for any incidences that might occur. Plan a route that will take you through a thoroughly lit area. Try to walk home in a group It can be easy to lose your friends when you are on a night out but having an action plan to stick together is a must. If someone tries to leave the group, make sure they don't go alone. People that move in groups are less likely to be the victims of any offense compared to those that are alone. Stay in touch with friends/family If you are in a situation where you are on your own, whether you have left or lost your group of friends, or are travelling back from somewhere at night, stay in touch with people. A quick message to a friend or family member to tell them you are safe goes a long way. Don't cause any unnecessary worry. Make phone-calls if necessary to help you feel more comfortable and safe when alone. Keep an eye on your locks Student areas are particularly prone to burglaries or crime so be vigilant with your locks. Always keep windows and doors locked when you leave the house, if you are home alone, and at night. If there are any problems with your locks report them immediately to your landlord to get them fixed straight away. Many landlords present keys with a label of your house number attached; it is a good idea to remove this in case you lose your keys. Place your belongings out of sight Leaving electrical or expensive equipment on show when you are not around the house is a temptation to the opportunist. As well as keeping windows and doors locked, consider putting your things out of plain sight. Insurance is a good thing to have at university because things can break or go missing all the time; Endsleigh offers tailored student insurance packages to suit your needs. (via NHS) Know your limits and be alcohol wise Going out with your friends and socialising is a big part of the university lifestyle. Being careless though can ruin an entire night and can often have very dangerous consequences. When you're at a bar, club or pub always keep an eye on your drink and refuse drinks from strangers. With the NHS announcing that every year hundreds of people are thought to be the victims of drinks spiking, as well as the increase in date rape drugs and rape cases, it is vital that you always keep an eye on your drink. Know your limits too and don't be pressurised into drinking something you don't want to. Have fun but stay safe. Don't invite strangers back Meeting someone when you are out, particularly under the influence of alcohol, can give you only a limited knowledge of that person. As trusting as they may seem, many people will take advantage of vulnerability. Whether you feel comfortable with them or not, don't invite a stranger back to your house. If you are interested in seeing that person again, arrange to meet somewhere public. Save emergency or late night numbers Have the numbers for your local services, safety watches or wardens saved in your phone. Trying to fumble around for a number that isn't there is the last thing you want. Know the late night services and schedules of your public transport options; if you are travelling alone on public transport don't sit in an empty carriage. Keep late night taxi numbers to hand too; never get into an unlicensed taxi though and always check that it is the correct vehicle before you enter. Make sure your hands are free If you are obstructed by an armful of books or other possessions you are an easy target. Have your hands free when you are walking or travelling alone at night. Many universities or self-defence programmes would advise carrying your keys in one hand just in case you need to defend yourself. Making a phone-call to feel safer is a good option but be aware of what is going on around you whilst you are on your mobile, and keep your other hand free. Listening to music or using a headset isn't recommended either as you are less likely to hear someone coming towards you. Above all here at Essay Writing Services we want you to get the most out of university. Make your university time memorable but in all the rights ways by following our guidance and taking particular care when you are out at night. For more tips and help on how to survive your first term at university, head to our blog. Our professional experts can help with any areas of academia from proofreading or advising on essays, to assisting with dissertations. Don't hesitate to contact us today.

16 Sweet Quotes About First Love

16 Sweet Quotes About First Love The first brush of love is a delicious feeling. You feel fresh energy surging in your body, and you become constantly aware of your own appearance, attitude, and behavior. The effect of new love may last for the courtship period, where both partners put their best foot forward. You enjoy the romantic overtures, the subtle body language, and the anticipation of passionate love. You could fall in love many times during the course of a lifetime, but the first rush of love always holds a special place in our hearts. The novelty of the feeling, like the first drops of dew on an untouched leaf, makes it special and unforgettable. These first love quotes develop on the theme of this treasured rush called first love. George Bernard Shaw First love is a little foolish and a lot of curiosity. Branislav Nusic First love is dangerous only when it is also the last. Rosemary Rogers First romance, first love, is something so special to all of us, both emotionally and physically, that it touches our lives and enriches them forever. Benjamin Disraeli The magic of first love is our ignorance that it can never end. Thomas Moore No, theres nothing half so sweet in life as loves young dream. Alfred Lord Tennyson In the spring a livelier iris changes on the burnished dove;In the spring a young mans fancy lightly turns to thoughts of love. Leo Buscaglia Love is always bestowed as a gift - freely, willingly, and without expectation... We dont love to be loved; we love to love. Blaise Pascal We conceal it from ourselves in vain: we must always love something. In those matters seemingly removed from love, the feeling is secretly to be found, and man cannot possibly live for a moment without it. Nietzsche Love is the state in which man sees things; most widely different from what they are. William Shakespeare As sweet and musicalAs bright Apollos lute, strung with his hair;And when Love speaks, the voice of all the godsMakes heaven drowsy with the harmony. Lady Murasaki The memories of long love gather like drifting snow, poignant as the mandarin ducks who float side by side in sleep. Leo Buscaglia The heart is the place where we live our passions. It is frail and easily broken, but wonderfully resilient. There is no point in trying to deceive the heart. It depends upon our honesty for its survival. Richard Garnett Sweet are the words of love, sweeter his thoughts:Sweetest of all what love nor says nor thinks. Bayard Taylor The loving are the daring. Francois Mauriac No love, no friendship, can cross the path of our destiny without leaving some mark on it forever. Alexander Smith ï » ¿Love is but the discovery of ourselves in others, and the delight in the recognition. Rekindle the Romance in Your Relationship First love is not just for first-time lovers. You can even feel the magic with your spouse. Some  couples  have claimed that every time they stay apart for a while, their reunion is as if they just met on a first date. Some  married couples  renew their  marriage  vows to rekindle the old flame. Have you felt the same way about your partner? If you havent, you need to rekindle the  romance and walk down memory lane. Visit romantic cities like Paris or Rome, and  fall in love  in the presence of the gods of love.

Merger, Acquisition, and International Strategies Essay - 9

Merger, Acquisition, and International Strategies - Essay Example The company under consideration is the Burger King. It also identifies a possible business level and corporate level strategies for the organization. The American Airline Group is a company that is publicly traded and has its headquarters in Texas. This company was formed on the 9th of December 2013, with a merger between the United States Airways Group, and the AMR Corporation. These two airline companies merged to form the largest airline company all over the world. The American Airline Group operates not less than 6,700 daily flights to different locations in the world. This covers about 56 countries, and more than 336 locations found in these 56 countries (Agyenim, 2014). The American airline group has operating revenue of about 40 billion American dollars, and boasts of a workforce of over 100,000 employees. The company plans to introduce an additional 607 aircrafts, and this includes 90 wide body airplanes, and 517 narrow body airplanes. The full merger of this company, resulting to the use of a single operating certificate is expected to be complete in the later periods of 2015 (Agyenim, 2014). The merger of the two airline companies was necessitated by the bankruptcy of AMR group. The strategy used in creating this merger is referred to as the stock-swap strategy/merger. Under this strategy, the shareholders of the US Airways received 28% of the shares of the new company. The creditors of AMR, and other equity holders were to receive the remaining 72% of the shares of the new company. This process was to take two years, upon which the company will pay the creditors of AMR their interests, and other stakeholders of the company a share of the company equity (Agyenim, 2014). This is a rare occurrence in bankruptcy cases where creditors usually receive cents, on a dollar they claim. On the other hand common stakeholders of the company are always wiped out, without receiving any benefits from the

Reading Response Questions for One.Life 8 & 9 Essay

Reading Response Questions for One.Life 8 & 9 - Essay Example In my view, the church is the perfect place to worship and pray. In addition, the church makes Christians have the desire to know more about the old devotional traditions of the Christian faith, and to become fully engaged in their renaissance today. There are various strengths and weaknesses in the church. Some of the strengths include the church enabling people explore how Jesus Christ prayed, how various denominations pray (Orthodox Christians, Anglicans and Roman Catholics) and how the Psalms teach Christians to pray. Other strengths of the church is empowering believers and making them understand that praying as a church is an important part of spiritual formation. The main weakness of the church is incorporating modernity into worship whereby God is no longer given the due respect as He was being given in the early church during the time of apostles of Christ. If I were in the capacity to change, I would ensure that every single believer follows the word of God to later, remaining holy since God is Holy. Chapter 9 of the book covers the life that believers lead in their ministry of serving God. According to the chapter, believers need to live a committed and dedicated life; however, they later get it hard to maintain the committed life (McKnight, 2010). The main reason as to why believers fail to maintain the life is the mixing of money and possessions with the church. I agree with the chapter since it speaks of the practical life that believers face every day. The chapter strikes me when it introduces the issue of leading a committed life and mixing possession and money with the church; something that drifts believers (me, for that matter) away from Jesus. There are various reasons that make people find the committed life difficult to follow. Such reasons include peer pressure whereby a believer with non-believer friends would be swayed away. In addition, some people have the

Dents Disease: Symptoms, Genetics, and Treatments

Dents Disease: Symptoms, Genetics, and Treatments Dents Disease Alessander Leyendecker Junior Clinical Aspects Dents disease is a recently characterized syndrome caused by a genetic mutation that leads to a renal tubular disorder and is characterized by manifestations of proximal tubule dysfunction. The proximal tubule is responsable for the reabsorption of sodium, potassium, calcium, glucose and low-molecular-weight proteins (like retinol binding protein and ÃŽ ±1 microglobulin and ÃŽ ²2 microglobulin) and for the secretion of ammonia, toxins, drugs and H+. Therefore, a proximal tubule dysfunction like Dents disease is characterized by low-molecular-weight proteinuria (excretion of low-molecular-weight proteins in the urine), hypercalcinuria (high concentration of calcium in the urine), nephocalcinosis (deposition of calcium salts in the renal parenchyma), nephrolithiasis (formation of crystalline aggregates that can develop anywhere along the urinary tract) and progressive renal failure. Low-molecular-weight proteinuria represents the most common symptom of Dents disease (Devuyst Thakker, 2010). Mapping: A higher disease severity in males and a lack of male to male transmission were identified by an analysis of 5 unrelated British families. The fact that females may show a milder phenotype suggests an X-linked recessive inheritance. The locus position on chromossome Xp11 was identified by linkage analysis of 2 3-generation families with Dent disease by Pook et al. (1993). Twenty X-linked polymorphic markers were used and the Linkage was established between Dents disease and the Xp1l 1 loci ARAFI (Z max = 5.42, 0 = 0.000), DXS426 (Z max = 3.61, 0 = 0.000), DXS255 (Z max = 5.48, 6 = 0.000) and DXS988 (Z max = 4.25, 0 = 0.045) to determine a locus order. In addition, DXS255 has presented a microdeletion in the affected members of one family, allowing the localization of Dents disease to Xp11.22 (Pook et al., 1993). Furthermore, another proximal renal tubular disorder associated with nephrolithiasis in a North American family and referred to as X-linked recessive nephrolithiasis has also been mapped to Xpl1.22. Suggesting that maybe there is one gene causing both X-linked recessive nephrolithiasis and Dents disease. Molecular Genetics: A study conducted by Fisher et al (1994) found a microdeletion in one Dent’s disease kindred, allowing the identification of the gene CLCN5 as a candidate. Furthermore, an investigation of 11 kindreds with renal tube disorders indentified 3 nonsense, 4 missense, 2 donor splice site mutations, 1 intragenic deletion and 1 microdeletion in CLCN5 gene (Llyod et al., 1996). Furthermore, Hoopes et al. (2005) indentified that some patients with Dents disease suffer from extra-renal symptoms such as cataract, mild intellectual impairment and hypotonia. Shared mutations in OCRL1 with the oculo-cerebrorenal syndrome of Lowe were identified in these patients. The presence of such extra-renal symptoms with mutations relating to Lowe syndrome is known as Dent disease 2. A research conducted by Bà ¶kenkamp et al. (2009) showed that low-molecular-weight proteinuria was a constant feature in all both Dent disease 1, Dent disease 2 and oculo-cerebrorenal syndrome of Lowe. However, there was a wide overlap in most of the other symptoms of the proximal tubulopathy. Nephrocalcinosis was observed more frequently in patients with Dents disease 1 than those with Dents disease 2 and Lowe syndrome; aminoaciduria, renal tubular acidosis, and renal failure was observed more frequently in patients with Lowe syndrome than patients with Dent-disease 1 and Dent disease disease 2. Genetics: All these findings have demonstrated that both Dent disease 1 and Dent disease 2 are a X-linked recessive inherited condition, caused by mutations in the OCRL1 (Dent disease 2) or CLCN5 (Dent disease 1) genes. These genes are located on chromosome Xp11.22 (Dent disease 1) and Xq25 (Dent disease 2). Mutation in CLCN5 are responsible for about 60% of the cases of Dent disease and mutation in OCRL are responsible for about 15% of the cases of Dent disease (Hoopes et al., 2004). So, nearly 25% of the cases of Dent disease do not have a known disease-causing mutation in OCRL or CLCN5, implying another genetic heterogeneity. Due to the fact that Dents disease is a X-linked recessive disorder, the disease is generally found in males only. Females carriers may show a milder phenotype. Furthermore, the disease may be present in early childhood (Devuyst Thakker, 2010). To date around 250 families with Dent-1 disease and about 50 patients with Dent-2 disease have been reported (Ludwig, Levtchenko Bà ¶kenkamp, 2014). The diagnosis of Dents disease is always difficult due to the wide variability of clinical presentation and, occasionally, lack of family history. Therefore, the disorder is likely underdiagnosed and the prevalence of this disease in the population is still unknown. More than 200 Dents disease 1 patients withCLCN5defects have been described with several different disease-causing mutations all over the gene. The types of mutations includes missense (44%) and nonsense (26%) mutations, small deletions/insertions (15%) and splice defects (11%), with a few hotspots, usually affecting arginine codons. Large insertions/deletions can be detected in around 4%of the patients. However, OCRLmutations in Dents disease 2 patients are not uniformly distributed. Missense mutations are usually found in exons 8–15 while nonsense or frameshift mutations very often affect exons (Ludwig, Levtchenko Bà ¶kenkamp, 2014). CLCN5 encodes the electrogenic Clà ¢Ã‚ Ã‚ »/H+ exchanger ClC-5. OCRL1 encodes a phosphatidylinositol bisphosphate (PIPà ¢Ã¢â‚¬Å¡Ã¢â‚¬Å¡) 5-phosphatase and mutations are also linked to the Lowe Syndrome. Mutations in any of these genes can culminate in the lack or dysfunction of these important proteins and result in the phenothype of Dents disease. Pathophysiology: The ability to reabsorb low-molecular-weight proteins and albumin that are ultrafiltered by the glomerulus are characteristics of the epithelial cells covering the proximal tubule portions of the nephron. This ability involves a process called receptor-mediated endocytosis. In the receptor-mediated endocytosis the particle to be endocytosed binds to specific receptor proteins concentrated at certain locations in the plasma membrane. Several types of receptors participate in the receptor-mediated endocytosis. These sites form a small depression in the plasma membrane that is covered by clathrin (a type of fibrous protein). After the binding of a ligand to plasma membrane-spanning receptors, a signal is sent through the membrane, leading to membrane coating, accumulation of the ligands into coated pits, and formation of a membrane invagination. The receptor and its ligand are then opsonized in clathrin-coated vesicles. The clathrin confers stability to the vesicle that are being transp orted into the cell. In the cytoplasm the vesicle loses its clathrin coverage and individual vesicles fuse to early endosomes. The acidification of endosomes by proton pumps ATP-dependent leads to the dissociation of the protein-receptor complex. This process allows the endosomes to fuse with the lysosomes through late endosomes. This acidification is reached by ATP-mediated transport of cytosolic H+ through the V-ATPase and demand an equal Cl conductance to preserve electroneutrality. It has been theorized that the H+ gradient can be neutralized by the C1C-5 action. In theory, ClC-5 provides an electrical shunt to neutralize the H+ gradient. Therefore, the vesicular acidification should be impaired by the loss of the endosomal Cl conductance mediated by ClC-5, resulting in the dysfunction of proximal tubule cells. To confirm this hypothesis, Piwon et al. (2000) created two distinct strains of ClC-5 knock-out (KO) mice which both have symptoms of the main characteristics of Dentâ₠¬â„¢s disease including manifestations of proximal tubule dysfunction like low-molecular-weight proteinuria. A reduced acidification of early endosomes in ClC-5-deficient mice have been demonstrated by in vitro experiments. However, ClC-5 is a 2Cl/H+ exchanger and not just a Cl channel, so the importance of this exchange activity for Dent’s disease was still unknown and needed to be assessed. In order to investigate this relevant question, Novarino et al. (2010) created a knock-in (KI) mouse presenting a point mutation in a important glutamate residue which transforms the exchanger into an uncoupled Cl channel that should help the endosomal acidification. The conventional ClC-5 KO mouse was subsequently compared with the KI mice. Acidification of the renal endosomes from wild-type and KI mice was regular, but greatly impaired in KO mice. Nevertheless, the same symptoms were indentified in both KI and KO mice, despite normal endosomal acidification and patients with Dentâ€⠄¢s disease, including low-molecular-weight proteinuria, hypercalciuria and hyperphosphaturia. Moreover, both the KI and KO mouse presented impaired proximal tubule endocytosis, indicating that proximal tubule dysfunction in Dent’s disease may happen in spite of the regular acidification of the endosomes. These findings indicate a function for a diminished endosomal Cl accumulation in Dent’s disease. Diagnosis: The clinical diagnosis of Dent’s disease is grounded on the presence of low-molecular-weight proteinuria, hypercalciuria, and at least one of the following characteristics: kidney stones, hematuria, nephrocalcinosis, renal insufficiency or hypophosphataemia (Hoopes et al., 2004). The clinical diagnosis can also be supported by nephrolithiasis and/or history of X-linked inheritance of renal Fanconi syndrome. The diagnosis can be confirmed by the recognition of mutation in both CLCN5 or OCRL1 by sequence analysis. Sequence analysis of affected males allows the identification of whole-gene deletions, multiexonic and exonic due to the lack of amplification is this case. Confirmation may also require deletion/duplication studies. It is imperative to previously identify the disease-causing mutation in the family when conducting a carrier test for at-risk relatives. The diagnosis of Dent disease 2, related with OCRL1 mutations, is more common than a diagnosis of Lowe syndrome when th ere are an absence of clinical symptoms and lack of severe intellectual deficit. Treatment: The reduction of hypercalciuria, prevention of nephrocalcinosis and kidney stones, and retardate the evolution of chronic kidney disease (nephrolithiasis) are the objectives of the current treatment. Thiazide diuretics in doses higher than 0.4 mg/kg/day have reducted urinary calcium excretion by more than 40% in males with Dent disease (Raja et al., 2002). However, side effects like hypokalemia, volume depletion, and cramping often occur. Similarly, we need to be cautious due to the fact that an increased hypercalciuria can result from the treatment of rickets with vitamin D. Furthermore, recent studies has been shown that a high citrate diet can slow the progression of chronic kidney disease in CLCN5 knockout mice (Cebotaru et al., 2005) and can be efficiently used to treat Dent disease. Genetic Counseling: The two types of Dent’s disease are X-linked. Therefore, men are affected more harshly. The father of an affected man will not have the disease or will he be a carrier of the mutation. The probability of transmitting the disease allele in each pregnancy is 50% if the mother of the proband is a carrier. Males who inherit the mutation will be affected and females who inherit the mutation will be carriers and will generally not be strongly affected. Affected men pass the disease-causing mutation to all of their daughters (who become carriers) and none of their sons. It is possible to conduct carrier testing for at-risk female relatives and prenatal testing for pregnancies at increased. Word count: 1673 References Blanchard A, Vargas-Poussou R, Peyrard S, Mogenet A, Baudouin V, Boudailliez B, Charbit M, Deschesnes G, Ezzhair N, Loirat C, Macher MA, Niaudet P, Azizi M: Effect of hydrochlorothiazide on urinary calcium excretion in Dent disease: an uncontrolled trial. Am J Kidney Dis 2008, 52:1084-1095. Bà ¶kenkamp A, Bà ¶ckenhauer D, Cheong HI, Hoppe B, Tasic V, Unwin R, Ludwig M. (2009). Dent-2 disease: A mild variant of Lowe Syndrome. J. Pediatr, 155, pp. 94-99, ISSN 0022-3476 Cebotaru V, Kaul S, Devuyst O, Cai H, Racusen L, Guggino WB, Guggino SE: High citrate diet delays progression of renal insufficiency in the ClC-5 knockout mouse model of Dent’s disease. Kidney Int 2005, 68:642-652. Devuyst, O., Thakker, R. V. (2010). Dent’s disease. Orphanet Journal of Rare Diseases. Fisher, S. E., Black, G. C., Lloyd, S. E., Hatchwell, E., Wrong, O., Thakker, R. V., Craig, I. W. (1994). Isolation and partial characterization of a chloride channel gene which is expressed in kidney and is a candidate for Dents disease (an X-linked hereditary nephrolithiasis). Human molecular genetics, 3(11), 2053-2060. Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS: Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochem Biophys Res Commun 2005, 329:941-946. Hoopes, R. R., Raja, K. M., Koich, A., Hueber, P., Reid, R., Knohl, S. J., Scheinman, S. J. (2004). Evidence for genetic heterogeneity in Dents disease.Kidney international,65(5), 1615-1620. Hoopes RR Jr, Shrimpton AE, Knohl SJ, Hueber P, Hoppe B, Matyus J, Simckes A, Tasic V, Toenshoff B, Suchy SF, Nussbaum RL, Scheinman SJ. Dent Disease with mutations in OCRL1. Am J Hum Genet. 2005;76:260–267. doi: 10.1086/427887. Ludwig, M., Levtchenko, E., Bà ¶kenkamp, A. (2014). Clinical utility gene card for: Dent disease (Dent-1 and Dent-2).European Journal of Human Genetics. Lloyd, S. E., Pearce, S. H., Fisher, S. E., Steinmeyer, K., Schwappach, B., Scheinman, S. J., Thakker, R. V. (1996). A common molecular basis for three inherited kidney stone diseases. Nature, 379(6564), 445-449. Novarino G, Weinert S, Rickheit G, Jentsch TJ: Endosomal chloride-proton exchange rather than chloride conductance is crucial for renal endocytosis. Science 2010, 328:1398-1401. Pagon, R. A., Adam, M. P., Bird, T. D., Dolan, C. R., Fong, C. T., Stephens, K., Rossetti, S. (2012). Dent Disease. Piwon N, Gunther W, Schwake M, Bà ¶sl MR, Jentsch TJ: ClC-5 Cl-channel disruption impairs endocytosis in a mouse model for Dent’s disease. Nature 2000, 408:369-373. Pook, M. A., Wrong, O., Wooding, C., Norden, A. G. W., Feest, T. G., Thakker, R. V. Dents disease, a renal Fanconi syndrome with nephrocalcinosis and kidney stones, is associated with a microdeletion involving DXS255 and maps to Xp11.22. Hum. Molec. Genet. 2: 2129-2134, 1993. Raja KA, Schurman S, DMello R G, Blowey D, Goodyer P, Van Why S, Ploutz-Snyder RJ, Asplin J, Scheinman SJ. Responsiveness of hypercalciuria to thiazide in Dents disease. J Am Soc Nephrol. 2002;13:2938–44 Wrong.O.M., Norden.A.G.W. and Feest.T.G. (1990) Quart. J. Med. 77, 1086-1087.

William Shakespeares Othello Essay -- William Shakespeare Othello Ess

William Shakespeare's Othello Every artist needs a subject to draw inspiration from—an idea to develop into a masterpiece. Leonardo da Vinci had Madame Lisa to portray in paint. The Beach Boys had Rhonda to render in rhyme. And William Shakespeare had one of one hundred stories written by Giraldi Cinthio to help him create his masterpiece, Othello. Each artist creates his own interpretation from his source. Shakespeare transformed the core of Cinthio’s story into a tragedy. A tragedy is drama which depicts â€Å"a public struggle between larger-than-life protagonists and universal forces† (Glossary 175). A tragedy also involves a â€Å"hero’s suffering and his consequent moments of tragic insight or knowledge† (McJannet 1). Each subtle change, which Shakespeare adapts from his source, serves to turn an ordinary tale into an extraordinary tragedy. The changes Shakespeare makes create a â€Å"larger-than-life protagonist.† In Cinthio’s work, the Ensign falls in love with Disdemona. The Ensign tries every means available to woo her, yet he fails in every attempt. The Ensign â€Å"imagined that the cause of his ill success was that Disdemona loved the Captain of the troop† (Cinthio 137). As a result, â€Å"the love which [the Ensign] had borne the lady now changed into the bitterest hate, and†¦he devoted all his thought to plot the death of the Captain of the troop and to divert the affection of the Moor from Disdemona† (Cinthio 137). Cinthio’s plot does not center on Othello, it is powered by Disdemona. Shakespeare makes a key change when creating his play. Shakespeare makes Othello the clear protagonist. Iago’s plotting revolves around Othello. Not only does Othello pass Iago over for a rightly deserved position, but â€Å"it is thought a... ...Michelangelo did with a chisel, so Shakespeare does with a pen. Shakespeare took Cinthio’s idea of a Moor. Shakespeare chipped away parts, and patched them back together, in a reconfiguration from his own mind’s eye. Shakespeare creates a tragic flaw, and from this a tragic error occurs. Shakespeare creates an impressive protagonist amid a fateful world. Within this tragic world, the fatal manipulation of Othello is brought to light. In short, Shakespeare turns a tale into a tragedy and a story into a masterpiece. Works Cited: Cinthio, Giraldi. Hecatommithi. Trans. J. E. Taylor. Ed. Alvin Kernan. New York: New American Library, 1998. (134-146). Glossary. (170-175). McJannet, Dr. Linda. â€Å"Short Paper: Shakespeare and Cinthio.† Spring, 2006. (1-2). Shakespeare, William. Othello. Ed. Alvin Kernan. New York: New American Library, 1998. (2-128).

Distribution Plan Essay

The distribution and delivery section of LEAPh Incorporation aims to satisfy and create values for the customers in which the company operates. The distinguishing characteristics of the business will be the combination of management experience, sales and distribution experience, high quality, innovative products and exceptional customer service. In particular, the Leading Philippines Incorporation will do a full service distribution servicing the customers in the market with a fulfilling assistance. In addition, the LEAPh Inc. will have an exclusive contract to distribute a new, groundbreaking product that would enable the company to gain immediate access to a majority of the potential customer base. The LEAPh Inc. intends to become a recognized distributor of one of a kind Digital Single-Lens Reflex Camera (DSLR) in the Philippines and become an internationally known locale brand. Leading Philippines Inc. plans to develop strong relationships with key customers so that the company will be viewed as an indispensable partner, rather than just another manufacturer. The company will work closely with each customer to recommend product assortment unique for their retail base, appropriate stocking levels, pricing and display assortments, as well as promotional ideas and material to increase sales. The LEAPh will seek out and work with the retailers that represent to deliver the most innovative and exciting products possible to the customers that will be served. In order for the products to be received by the customers, the LEAPh will be going to distribute the cameras through sales representatives and through retail stores as well. The company will be using a three level distribution channel. In a three level channel structure, the retailers serve as intermediaries between the consumers and the manufacturer which is the LEAPh. Retailers order products directly from the manufacturer, and then sell those products directly to the consumers. This will enable the company to stay in touch with the retailers up to the end users of the products and understand their tastes, preferences and tendencies. This will also help the company to minimize the total distribution costs for the given products. MANUFACTURER RETAILERS CUSTOMERS Leading Philippines Inc. Department Stores Customers The intermediaries which are the retailer’s outlets provide several benefits to both manufacturers and consumers. It will improve the efficiency of the company; make a better assortment of products, the reutilization of transactions, and easier searching for goods as well as customers. The use of this level of distribution will also aid the search processes of both the buyers and sellers. Producers are searching to determine their customers’ needs, while customers are searching for certain products and services. A degree of uncertainty in both search processes can be reduced by using this channel of distribution. For example, consumers are more likely to find what they are looking for when they shop at retail institutions organized by separate lines of trade, such as grocery, hardware, and clothing store. In addition, producers can make some of their commonly used products more widely available by placing them in many different retail outlets, so that consumers are more likely to find them at the right time. The company will be implementing an individualized customer service which will provide the customers with what they want, when and how they want it with the help of the retailers. This fully integrated program for the customers will help the company to increase its sales through innovations of the products, creating promotions, advertising, custom marketing material and the word of mouth from its customers. In this way, the company has the full control over the distribution of the products as well. Here are the methods that will be used in this level of channel distribution of the products from Leading Philippines Inc.: †¢ Selling of products through the leading retail outlets and department stores nationwide. †¢ Selling the products by the orders that are received by telephone, email and fax which is also known as telemarketing. ( Made possible by advertising the products through websites) This stage of distribution channel will also be use in order for the products to be widely available in all leading department stores and retailer’s shops nationwide. And to optimize the product launch as well. The LEAPh will employ an intensive distribution to the customers so that the products could be distributed from as many department stores and retailers ‘outlets as possible to provide a location convenience for its consumers. It will also increase the sales of the company, and provide wider customer recognition. By communicating and building relationships with the members at each step in the channel, there should be a proper communication throughout the channel and every member in the channel should contribute for a healthy relationship. Transparency should be maintained throughout the channel.